Onset of Carbon Catabolite Repression in Aspergillus nidulans
نویسندگان
چکیده
منابع مشابه
Onset of carbon catabolite repression in Aspergillus nidulans. Parallel involvement of hexokinase and glucokinase in sugar signaling.
The role of hexose phosphorylating enzymes in the signaling of carbon catabolite repression was investigated in the filamentous fungus Aspergillus nidulans. A d-fructose non-utilizing, hexokinase-deficient (hxkA1, formerly designated frA1) strain was utilized to obtain new mutants lacking either glucokinase (glkA4) or both hexose kinases (hxkA1/glkA4). d-Glucose and d-fructose phosphorylation i...
متن کاملOnset of Carbon Catabolite Repression in Aspergillus nidulans: Parallel Involvement of Hexokinase and Glucokinase in Sugar Signalling*
* This work was supported by the Centre National de la Recherche Scientifique (UMR 8621), the Université Paris-Sud XI and the European Community, grants BIO4-CT96-0535 and QLK3-CT99-00729. d These authors (MF & PJIvdV) contributed equally to this work. e Present address (PJIvdV): Laboratory of Phytopathology, Wageningen University, Binnenhaven 5, NL-6709 PD Wageningen, The Netherlands. f Presen...
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Control of gene expression is a basic regulatory mechanism of living organisms. In microorganisms, glucose or other rapidly metabolizable carbon sources repress the expression of genes that code for enzymes related to the metabolism of other carbon sources. This phenomenon, known as catabolite repression, allows microorganisms to cope effectively with changes in the carbon sources present in th...
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Carbon catabolite repression (CCR) is a process that selects the energetically most favorable carbon source in an environment. CCR represses the use of less favorable carbon sources when a better source is available. Glucose is the preferential carbon source for most microorganisms because it is rapidly metabolized, generating quick energy for growth. In the filamentous fungus Aspergillus nidul...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2003
ISSN: 0021-9258
DOI: 10.1074/jbc.m209443200